Control of RAB7 activity and localization through the retromer‐TBC1D5 complex enables RAB7‐dependent mitophagy

Retromer is an endosomal multi‐protein complex that organizes the endocytic recycling of a vast range of integral membrane proteins. Here, we establish an additional retromer function in controlling the activity and localization of the late endosomal small GTPase RAB7. Surprisingly, we found that RA...

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Detalles Bibliográficos
Autores principales: Jimenez‐Orgaz, Ana, Kvainickas, Arunas, Nägele, Heike, Denner, Justin, Eimer, Stefan, Dengjel, Jörn, Steinberg, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770787/
https://www.ncbi.nlm.nih.gov/pubmed/29158324
http://dx.doi.org/10.15252/embj.201797128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770787/
https://www.ncbi.nlm.nih.gov/pubmed/29158324
http://dx.doi.org/10.15252/embj.201797128

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