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Parkinson's Disease Skin Fibroblasts Display Signature Alterations in Growth, Redox Homeostasis, Mitochondrial Function, and Autophagy

The discovery of biomarkers for Parkinson's disease (PD) is challenging due to the heterogeneous nature of this disorder, and a poor correlation between the underlying pathology and the clinically expressed phenotype. An ideal biomarker would inform on PD-relevant pathological changes via an ea...

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Detalles Bibliográficos
Autores principales: Teves, Joji M. Y., Bhargava, Vedanshi, Kirwan, Konner R., Corenblum, Mandi J., Justiniano, Rebecca, Wondrak, Georg T., Anandhan, Annadurai, Flores, Andrew J., Schipper, David A., Khalpey, Zain, Sligh, James E., Curiel-Lewandrowski, Clara, Sherman, Scott J., Madhavan, Lalitha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770791/
https://www.ncbi.nlm.nih.gov/pubmed/29379409
http://dx.doi.org/10.3389/fnins.2017.00737