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Progress and Challenges in the Design and Clinical Development of Antibodies for Cancer Therapy
The remarkable progress in engineering and clinical development of therapeutic antibodies in the last 40 years, after the seminal work by Köhler and Milstein, has led to the approval by the United States Food and Drug Administration (FDA) of 21 antibodies for cancer immunotherapy. We review here the...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770808/ https://www.ncbi.nlm.nih.gov/pubmed/29379493 http://dx.doi.org/10.3389/fimmu.2017.01751 |