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Mechanistic Insights into Regulation of JAK2 Tyrosine Kinase
JAK2 is a member of the Janus kinase (JAKs) family of non-receptor protein tyrosine kinases, which includes JAK1–3 and TYK2. JAKs serve as the cytoplasmic signaling components of cytokine receptors and are activated through cytokine-mediated trans-phosphorylation, which leads to receptor phosphoryla...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770812/ https://www.ncbi.nlm.nih.gov/pubmed/29379470 http://dx.doi.org/10.3389/fendo.2017.00361 |