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Movement decline across lifespan of Caenorhabditis elegans mutants in the insulin/insulin‐like signaling pathway

Research in aging biology has identified several pathways that are molecularly conserved across species that extend lifespan when mutated. The insulin/insulin‐like signaling (IIS) pathway is one of the most widely studied of these. It has been assumed that extending lifespan also extends healthspan...

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Detalles Bibliográficos
Autores principales: Newell Stamper, Breanne L., Cypser, James R., Kechris, Katerina, Kitzenberg, David Alan, Tedesco, Patricia M., Johnson, Thomas E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770877/
https://www.ncbi.nlm.nih.gov/pubmed/29214707
http://dx.doi.org/10.1111/acel.12704