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Interplay of pathogenic forms of human tau with different autophagic pathways

Loss of neuronal proteostasis, a common feature of the aging brain, is accelerated in neurodegenerative disorders, including different types of tauopathies. Aberrant turnover of tau, a microtubule‐stabilizing protein, contributes to its accumulation and subsequent toxicity in tauopathy patients’ bra...

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Detalles Bibliográficos
Autores principales: Caballero, Benjamin, Wang, Yipeng, Diaz, Antonio, Tasset, Inmaculada, Juste, Yves Robert, Stiller, Barbara, Mandelkow, Eva‐Maria, Mandelkow, Eckhard, Cuervo, Ana Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770880/
https://www.ncbi.nlm.nih.gov/pubmed/29024336
http://dx.doi.org/10.1111/acel.12692