pKID Binds to KIX via an Unstructured Transition State with Nonnative Interactions

Understanding the detailed mechanism of interaction of intrinsically disordered proteins with their partners is crucial to comprehend their functions in signaling and transcription. Through its interaction with KIX, the disordered pKID region of CREB protein is central in the transcription of cAMP r...

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Detalles Bibliográficos
Autores principales: Dahal, Liza, Kwan, Tristan O.C., Shammas, Sarah L., Clarke, Jane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2017
Materias:
Proteins
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770965/
https://www.ncbi.nlm.nih.gov/pubmed/29262364
http://dx.doi.org/10.1016/j.bpj.2017.10.016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770965/
https://www.ncbi.nlm.nih.gov/pubmed/29262364
http://dx.doi.org/10.1016/j.bpj.2017.10.016

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