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pKID Binds to KIX via an Unstructured Transition State with Nonnative Interactions
Understanding the detailed mechanism of interaction of intrinsically disordered proteins with their partners is crucial to comprehend their functions in signaling and transcription. Through its interaction with KIX, the disordered pKID region of CREB protein is central in the transcription of cAMP r...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Biophysical Society
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770965/ https://www.ncbi.nlm.nih.gov/pubmed/29262364 http://dx.doi.org/10.1016/j.bpj.2017.10.016 |