Phosphorylation of the IDP KID Modulates Affinity for KIX by Increasing the Lifetime of the Complex

Intrinsically disordered proteins (IDPs) are known to undergo a range of posttranslational modifications, but by what mechanism do such modifications affect the binding of an IDP to its partner protein? We investigate this question using one such IDP, the kinase inducible domain (KID) of the transcr...

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Detalles Bibliográficos
Autores principales: Dahal, Liza, Shammas, Sarah L., Clarke, Jane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2017
Materias:
Proteins
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770967/
https://www.ncbi.nlm.nih.gov/pubmed/29262363
http://dx.doi.org/10.1016/j.bpj.2017.10.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770967/
https://www.ncbi.nlm.nih.gov/pubmed/29262363
http://dx.doi.org/10.1016/j.bpj.2017.10.015

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