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M2-polarized tumor-associated macrophages facilitated migration and epithelial-mesenchymal transition of HCC cells via the TLR4/STAT3 signaling pathway

BACKGROUND: M2-polarized macrophages are tumor-associated-macrophages (TAMs), which are important contents of tumor-infiltrating immune cells. Toll-like receptor 4 (TLR4) is a molecular biomarker of tumor aggressiveness and poor prognosis. Toll-like receptors (TLRs) have important roles in the immun...

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Detalles Bibliográficos
Autores principales: Yao, Rong-Rong, Li, Jing-Huan, Zhang, Rui, Chen, Rong-Xin, Wang, Yan-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771014/
https://www.ncbi.nlm.nih.gov/pubmed/29338742
http://dx.doi.org/10.1186/s12957-018-1312-y