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Interleukin-6 induces fat loss in cancer cachexia by promoting white adipose tissue lipolysis and browning

BACKGROUND: Cancer cachexia is a progressive and multi-factorial metabolic syndrome characterized by loss of adipose tissue and skeletal muscle. White adipose tissue (WAT) lipolysis and white-to-brown transdifferentiation of WAT (WAT browning) are proposed to contribute to WAT atrophy in cancer cach...

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Detalles Bibliográficos
Autores principales: Han, Jun, Meng, Qingyang, Shen, Lei, Wu, Guohao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771021/
https://www.ncbi.nlm.nih.gov/pubmed/29338749
http://dx.doi.org/10.1186/s12944-018-0657-0