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New Psychoactive Substances 3-Methoxyphencyclidine (3-MeO-PCP) and 3-Methoxyrolicyclidine (3-MeO-PCPy): Metabolic Fate Elucidated with Rat Urine and Human Liver Preparations and their Detectability in Urine by GC-MS, “LC-(High Resolution)-MS(n)” and “LC-(High Resolution)-MS/MS”

BACKGROUND: 3-Methoxyphencyclidine (3-MeO-PCP) and 3-methoxyrolicyclidine (3-MeO-PCPy) are two new psychoactive substances (NPS). The aims of the present study were the elucidation of their metabolic fate in rat and pooled human liver microsomes (pHLM) the identification of the cytochrome P450 (CYP)...

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Detalles Bibliográficos
Autores principales: Michely, Julian A., Manier, Sascha K., Caspar, Achim T., Brandt, Simon D., Wallach, Jason, Maurer, Hans. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771046/
https://www.ncbi.nlm.nih.gov/pubmed/27758707
http://dx.doi.org/10.2174/1570159X14666161018151716