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New Psychoactive Substances 3-Methoxyphencyclidine (3-MeO-PCP) and 3-Methoxyrolicyclidine (3-MeO-PCPy): Metabolic Fate Elucidated with Rat Urine and Human Liver Preparations and their Detectability in Urine by GC-MS, “LC-(High Resolution)-MS(n)” and “LC-(High Resolution)-MS/MS”
BACKGROUND: 3-Methoxyphencyclidine (3-MeO-PCP) and 3-methoxyrolicyclidine (3-MeO-PCPy) are two new psychoactive substances (NPS). The aims of the present study were the elucidation of their metabolic fate in rat and pooled human liver microsomes (pHLM) the identification of the cytochrome P450 (CYP)...
Autores principales: | Michely, Julian A., Manier, Sascha K., Caspar, Achim T., Brandt, Simon D., Wallach, Jason, Maurer, Hans. H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bentham Science Publishers
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771046/ https://www.ncbi.nlm.nih.gov/pubmed/27758707 http://dx.doi.org/10.2174/1570159X14666161018151716 |
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