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A rapid high-resolution method for resolving DNA topoisomers

OBJECTIVE: Agarose gel electrophoresis has been the mainstay technique for the analysis of DNA samples of moderate size. In addition to separating linear DNA molecules, it can also resolve different topological forms of plasmid DNAs, an application useful for the analysis of the reactions of DNA top...

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Detalles Bibliográficos
Autores principales: Mitchenall, Lesley A., Hipkin, Rachel E., Piperakis, Michael M., Burton, Nicolas P., Maxwell, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771066/
https://www.ncbi.nlm.nih.gov/pubmed/29338757
http://dx.doi.org/10.1186/s13104-018-3147-6