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Benefits of VCE-003.2, a cannabigerol quinone derivative, against inflammation-driven neuronal deterioration in experimental Parkinson’s disease: possible involvement of different binding sites at the PPARγ receptor

BACKGROUND: Neuroprotection with cannabinoids in Parkinson’s disease (PD) has been afforded predominantly with antioxidant or anti-inflammatory cannabinoids. In the present study, we investigated the anti-inflammatory and neuroprotective properties of VCE-003.2, a quinone derivative of the non-psych...

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Detalles Bibliográficos
Autores principales: García, Concepción, Gómez-Cañas, María, Burgaz, Sonia, Palomares, Belén, Gómez-Gálvez, Yolanda, Palomo-Garo, Cristina, Campo, Sara, Ferrer-Hernández, Joel, Pavicic, Carolina, Navarrete, Carmen, Luz Bellido, M., García-Arencibia, Moisés, Ruth Pazos, M., Muñoz, Eduardo, Fernández-Ruiz, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771072/
https://www.ncbi.nlm.nih.gov/pubmed/29338785
http://dx.doi.org/10.1186/s12974-018-1060-5