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CDK16 Phosphorylates and Degrades p53 to Promote Radioresistance and Predicts Prognosis in Lung Cancer

Rationale: Radioresistance is considered the main cause of local relapse in lung cancer. However, the molecular mechanisms of radioresistance remain poorly understood. This study investigates the role of CDK16 in radioresistance of human lung cancer cells. Methods: The expression levels of CDK16 wer...

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Detalles Bibliográficos
Autores principales: Xie, Jie, Li, Yan, Jiang, Ke, Hu, Kaishun, Zhang, Sheng, Dong, Xiaorong, Dai, Xiaofang, Liu, Li, Zhang, Tao, Yang, Kunyu, Huang, Kai, Chen, Junjie, Shi, Shaojun, Zhang, Yu, Wu, Gang, Xu, Shuangbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771083/
https://www.ncbi.nlm.nih.gov/pubmed/29344296
http://dx.doi.org/10.7150/thno.21963