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Molecular and functional signatures in a novel Alzheimer’s disease mouse model assessed by quantitative proteomics

BACKGROUND: Alzheimer’s disease (AD), the most common neurodegenerative disorder, is characterized by the deposition of extracellular amyloid plaques and intracellular neurofibrillary tangles. To understand the pathological mechanisms underlying AD, developing animal models that completely encompass...

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Detalles Bibliográficos
Autores principales: Kim, Dong Kyu, Park, Joonho, Han, Dohyun, Yang, Jinhee, Kim, Ahbin, Woo, Jongmin, Kim, Youngsoo, Mook-Jung, Inhee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771139/
https://www.ncbi.nlm.nih.gov/pubmed/29338754
http://dx.doi.org/10.1186/s13024-017-0234-4