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Gremlin Regulates Podocyte Apoptosis via Transforming Growth Factor-β (TGF-β) Pathway in Diabetic Nephropathy

BACKGROUND: Gremlin has been reported to be up-regulated in glomerular mesangial cells in diabetic nephropathy (DN). However, the regulation of gremlin in podocytes is still rarely reported. This study aimed to investigate the underlying mechanisms by which gremlin mediates the pathogenesis of DN vi...

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Detalles Bibliográficos
Autores principales: Wang, Xiao-Bing, Zhu, Hong, Song, Wei, Su, Jian-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771160/
https://www.ncbi.nlm.nih.gov/pubmed/29315280
http://dx.doi.org/10.12659/MSM.905758