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Palmitate-induced insulin resistance is attenuated by Pioglitazone and EGCG through reducing the gluconeogenic key enzymes expression in HepG2 cells

Hypothesis: Palmitate causes insulin resistance (IR) in insulin target tissue. Pioglitazone (an anti-hyperglycemic agent) and epigallocatechin gallate (EGCG, a dietary supplement) can be used for the treatment of type 2 diabetes. However, their molecular effects on gluconeogenesis remain unclear. Ob...

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Detalles Bibliográficos
Autores principales: Yadollah, S, Kazemipour, N, Bakhtiyari, S, Nazifi, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Carol Davila University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771254/
https://www.ncbi.nlm.nih.gov/pubmed/29362600