A single nucleotide polymorphism in CYP1B1 leads to differential prostate cancer risk and telomere length

BACKGROUND: Cytochrome P450 1B1 (CYP1B1) is a key enzyme in its oestrogen metabolism pathway, giving rise to hydroxylation and conjugation. Functionally relevant genetic variants within CYP1B1 may affect the telomere length and subsequently lead to prostate carcinogenesis. METHODS: We evaluated 8 CY...

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Detalles Bibliográficos
Autores principales: Gu, Cheng-Yuan, Li, Gao-Xiang, Zhu, Yu, Xu, Hua, Zhu, Yao, Qin, Xiao-Jian, Bo, Dai, Ye, Ding-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771334/
https://www.ncbi.nlm.nih.gov/pubmed/29344273
http://dx.doi.org/10.7150/jca.21774

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771334/
https://www.ncbi.nlm.nih.gov/pubmed/29344273
http://dx.doi.org/10.7150/jca.21774

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