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Ghrelin deletion protects against age‐associated hepatic steatosis by downregulating the C/EBPα‐p300/DGAT1 pathway

Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease worldwide. NAFLD usually begins as low‐grade hepatic steatosis which further progresses in an age‐dependent manner to nonalcoholic steatohepatitis (NASH), fibrosis, cirrhosis, and hepatocellular carcinoma in some patients. Ghr...

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Detalles Bibliográficos
Autores principales: Guillory, Bobby, Jawanmardi, Nicole, Iakova, Polina, Anderson, Barbara, Zang, Pu, Timchenko, Nikolai A., Garcia, Jose M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771394/
https://www.ncbi.nlm.nih.gov/pubmed/29024407
http://dx.doi.org/10.1111/acel.12688