DLP1‐dependent mitochondrial fragmentation and redistribution mediate prion‐associated mitochondrial dysfunction and neuronal death

Mitochondrial malfunction is a universal and critical step in the pathogenesis of many neurodegenerative diseases including prion diseases. Dynamin‐like protein 1 (DLP1) is one of the key regulators of mitochondrial fission. In this study, we investigated the role of DLP1 in mitochondrial fragmentat...

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Detalles Bibliográficos
Autores principales: Li, Chaosi, Wang, Di, Wu, Wei, Yang, Wei, Ali Shah, Syed Zahid, Zhao, Ying, Duan, Yuhan, Wang, Lu, Zhou, Xiangmei, Zhao, Deming, Yang, Lifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771399/
https://www.ncbi.nlm.nih.gov/pubmed/29166700
http://dx.doi.org/10.1111/acel.12693

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771399/
https://www.ncbi.nlm.nih.gov/pubmed/29166700
http://dx.doi.org/10.1111/acel.12693

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