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SIRT3 deregulation is linked to mitochondrial dysfunction in Alzheimer's disease

Alzheimer's disease (AD) is the leading cause of dementia in the elderly. Despite decades of study, effective treatments for AD are lacking. Mitochondrial dysfunction has been closely linked to the pathogenesis of AD, but the relationship between mitochondrial pathology and neuronal damage is p...

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Detalles Bibliográficos
Autores principales: Lee, Junghee, Kim, Yunha, Liu, Tian, Hwang, Yu Jin, Hyeon, Seung Jae, Im, Hyeonjoo, Lee, Kyungeun, Alvarez, Victor E., McKee, Ann C., Um, Soo‐Jong, Hur, Manwook, Mook‐Jung, Inhee, Kowall, Neil W., Ryu, Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771400/
https://www.ncbi.nlm.nih.gov/pubmed/29130578
http://dx.doi.org/10.1111/acel.12679