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SIRT3 deregulation is linked to mitochondrial dysfunction in Alzheimer's disease
Alzheimer's disease (AD) is the leading cause of dementia in the elderly. Despite decades of study, effective treatments for AD are lacking. Mitochondrial dysfunction has been closely linked to the pathogenesis of AD, but the relationship between mitochondrial pathology and neuronal damage is p...
Autores principales: | Lee, Junghee, Kim, Yunha, Liu, Tian, Hwang, Yu Jin, Hyeon, Seung Jae, Im, Hyeonjoo, Lee, Kyungeun, Alvarez, Victor E., McKee, Ann C., Um, Soo‐Jong, Hur, Manwook, Mook‐Jung, Inhee, Kowall, Neil W., Ryu, Hoon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771400/ https://www.ncbi.nlm.nih.gov/pubmed/29130578 http://dx.doi.org/10.1111/acel.12679 |
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