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Synthesis, Biological Evaluation and Modeling Studies of New Pyrido[3,4-b]indole Derivatives as Broad-Spectrum Potent Anticancer Agents

OBJECTIVE: There is an urgent need drugs against particularly difficult to treat solid tumors such as pancreatic, triple negative breast, lung, colon, metastatic prostate cancers and melanoma. Thus, the objective of this study was to synthesize compounds based computational modeling that indicated t...

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Detalles Bibliográficos
Autores principales: Patil, Shivaputra A, Addo, James K, Deokar, Hemantkumar, Sun, Shan, Wang, Jin, Li, Wei, Suttle, D Parker, Wang, Wei, Zhang, Ruiwen, Buolamwini, John K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771418/
https://www.ncbi.nlm.nih.gov/pubmed/29354330
http://dx.doi.org/10.4172/2169-0138.1000143