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Redefining the endophenotype concept to accommodate transdiagnostic vulnerabilities and etiological complexity
In psychopathology research, endophenotypes are a subset of biomarkers that indicate genetic vulnerability independent of clinical state. To date, an explicit expectation is that endophenotypes be specific to single disorders. We evaluate this expectation considering recent advances in psychiatric g...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Future Medicine Ltd
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771461/ https://www.ncbi.nlm.nih.gov/pubmed/28891303 http://dx.doi.org/10.2217/bmm-2017-0002 |