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Determination of 2,4-Dichlorophenoxyacetic acid (2,4-D) in rat serum for pharmacokinetic studies with a simple HPLC method

2,4-Dichlorophenoxyacetic acid (2,4-D) is a chlorophenoxy herbicide used worldwide. We describe a high-performance liquid chromatography (HPLC) method with UV detection for the determination of 2,4-D in female and male rat serum. This allows to observe the change of serum 2,4-D concentration in rats...

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Detalles Bibliográficos
Autores principales: Chen, Xiao, Zhang, Hongling, Wan, Yanjian, Chen, Xi, Li, Yuanyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771594/
https://www.ncbi.nlm.nih.gov/pubmed/29342170
http://dx.doi.org/10.1371/journal.pone.0191149