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Regulation of circadian clock transcriptional output by CLOCK:BMAL1

The mammalian circadian clock relies on the transcription factor CLOCK:BMAL1 to coordinate the rhythmic expression of 15% of the transcriptome and control the daily regulation of biological functions. The recent characterization of CLOCK:BMAL1 cistrome revealed that although CLOCK:BMAL1 binds synchr...

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Detalles Bibliográficos
Autores principales: Trott, Alexandra J., Menet, Jerome S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771620/
https://www.ncbi.nlm.nih.gov/pubmed/29300726
http://dx.doi.org/10.1371/journal.pgen.1007156