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Combinations of registered drugs reduce treatment times required to deplete Wolbachia in the Litomosoides sigmodontis mouse model

Filarial parasites can be targeted by antibiotic treatment due to their unique endosymbiotic relationship with Wolbachia bacteria. This finding has led to successful treatment strategies in both, human onchocerciasis and lymphatic filariasis. A 4–6 week treatment course using doxycycline results in...

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Detalles Bibliográficos
Autores principales: Specht, Sabine, Pfarr, Kenneth M., Arriens, Sandra, Hübner, Marc P., Klarmann-Schulz, Ute, Koschel, Marianne, Sternberg, Sonja, Martin, Coralie, Ford, Louise, Taylor, Mark J., Hoerauf, Achim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771630/
https://www.ncbi.nlm.nih.gov/pubmed/29300732
http://dx.doi.org/10.1371/journal.pntd.0006116