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Internal genes of a highly pathogenic H5N1 influenza virus determine high viral replication in myeloid cells and severe outcome of infection in mice

The highly pathogenic avian influenza (HPAI) H5N1 influenza virus has been a public health concern for more than a decade because of its frequent zoonoses and the high case fatality rate associated with human infections. Severe disease following H5N1 influenza infection is often associated with dysr...

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Detalles Bibliográficos
Autores principales: Li, Hui, Bradley, Konrad C., Long, Jason S., Frise, Rebecca, Ashcroft, Jonathan W., Hartgroves, Lorian C., Shelton, Holly, Makris, Spyridon, Johansson, Cecilia, Cao, Bin, Barclay, Wendy S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771632/
https://www.ncbi.nlm.nih.gov/pubmed/29300777
http://dx.doi.org/10.1371/journal.ppat.1006821