Alternative RNA splicing in the endothelium mediated in part by Rbfox2 regulates the arterial response to low flow

Low and disturbed blood flow drives the progression of arterial diseases including atherosclerosis and aneurysms. The endothelial response to flow and its interactions with recruited platelets and leukocytes determine disease progression. Here, we report widespread changes in alternative splicing of...

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Detalles Bibliográficos
Autores principales: Murphy, Patrick A, Butty, Vincent L, Boutz, Paul L, Begum, Shahinoor, Kimble, Amy L, Sharp, Phillip A, Burge, Christopher B, Hynes, Richard O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771670/
https://www.ncbi.nlm.nih.gov/pubmed/29293084
http://dx.doi.org/10.7554/eLife.29494

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771670/
https://www.ncbi.nlm.nih.gov/pubmed/29293084
http://dx.doi.org/10.7554/eLife.29494

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