Tensile forces drive a reversible fibroblast-to-myofibroblast transition during tissue growth in engineered clefts

Myofibroblasts orchestrate wound healing processes, and if they remain activated, they drive disease progression such as fibrosis and cancer. Besides growth factor signaling, the local extracellular matrix (ECM) and its mechanical properties are central regulators of these processes. It remains unkn...

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Detalles Bibliográficos
Autores principales: Kollmannsberger, Philip, Bidan, Cécile M., Dunlop, John W. C., Fratzl, Peter, Vogel, Viola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771696/
https://www.ncbi.nlm.nih.gov/pubmed/29349300
http://dx.doi.org/10.1126/sciadv.aao4881

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771696/
https://www.ncbi.nlm.nih.gov/pubmed/29349300
http://dx.doi.org/10.1126/sciadv.aao4881

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