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Tensile forces drive a reversible fibroblast-to-myofibroblast transition during tissue growth in engineered clefts
Myofibroblasts orchestrate wound healing processes, and if they remain activated, they drive disease progression such as fibrosis and cancer. Besides growth factor signaling, the local extracellular matrix (ECM) and its mechanical properties are central regulators of these processes. It remains unkn...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Association for the Advancement of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771696/ https://www.ncbi.nlm.nih.gov/pubmed/29349300 http://dx.doi.org/10.1126/sciadv.aao4881 |