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Delayed neutrophil apoptosis enhances NET formation in cystic fibrosis

BACKGROUND: Cystic fibrosis (CF) lung disease is defined by large numbers of neutrophils and associated damaging products in the airway. Delayed neutrophil apoptosis is described in CF although it is unclear whether this is a primary neutrophil defect or a response to chronic inflammation. Increased...

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Detalles Bibliográficos
Autores principales: Gray, Robert D, Hardisty, Gareth, Regan, Kate H, Smith, Maeve, Robb, Calum T, Duffin, Rodger, Mackellar, Annie, Felton, Jennifer M, Paemka, Lily, McCullagh, Brian N, Lucas, Christopher D, Dorward, David A, McKone, Edward F, Cooke, Gordon, Donnelly, Seamas C, Singh, Pradeep K, Stoltz, David A, Haslett, Christopher, McCray, Paul B, Whyte, Moira K B, Rossi, Adriano G, Davidson, Donald J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771859/
https://www.ncbi.nlm.nih.gov/pubmed/28916704
http://dx.doi.org/10.1136/thoraxjnl-2017-210134