Inhibiting mitochondrial phosphate transport as an unexploited antifungal strategy

The development of effective antifungal therapeutics remains a formidable challenge due to the close evolutionary relationship between humans and fungi. Mitochondrial function may present an exploitable vulnerability due to its differential utilization in fungi and its pivotal roles in fungal morpho...

Descripción completa

Detalles Bibliográficos
Autores principales: McLellan, Catherine A., Vincent, Benjamin M., Solis, Norma V., Lancaster, Alex K., Sullivan, Lucas B., Hartland, Cathy L., Youngsaye, Willmen, Filler, Scott G., Whitesell, Luke, Lindquist, Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771894/
https://www.ncbi.nlm.nih.gov/pubmed/29227471
http://dx.doi.org/10.1038/nchembio.2534

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771894/
https://www.ncbi.nlm.nih.gov/pubmed/29227471
http://dx.doi.org/10.1038/nchembio.2534

Ejemplares similares