Cargando…
Inhibiting mitochondrial phosphate transport as an unexploited antifungal strategy
The development of effective antifungal therapeutics remains a formidable challenge due to the close evolutionary relationship between humans and fungi. Mitochondrial function may present an exploitable vulnerability due to its differential utilization in fungi and its pivotal roles in fungal morpho...
Autores principales: | McLellan, Catherine A., Vincent, Benjamin M., Solis, Norma V., Lancaster, Alex K., Sullivan, Lucas B., Hartland, Cathy L., Youngsaye, Willmen, Filler, Scott G., Whitesell, Luke, Lindquist, Susan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771894/ https://www.ncbi.nlm.nih.gov/pubmed/29227471 http://dx.doi.org/10.1038/nchembio.2534 |
Ejemplares similares
-
ML212: A small-molecule probe for investigating fluconazole resistance mechanisms in Candida albicans
por: Youngsaye, Willmen, et al.
Publicado: (2013) -
Unexploited features of the calorimeter
por: Drijard, D, et al.
Publicado: (1992) -
Unexploited opportunities for phage therapy
por: Oliveira, Hugo, et al.
Publicado: (2015) -
Fusion transcripts: Unexploited vulnerabilities in cancer?
por: Neckles, Carla, et al.
Publicado: (2019) -
COVID-19 Prediction Models and Unexploited Data
por: Santosh, K. C.
Publicado: (2020)