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Age-related oxidative changes in pancreatic islets are predominantly located in the vascular system

Aged tissues usually show a decreased regenerative capacity accompanied by a decline in functionality. During aging pancreatic islets also undergo several morphological and metabolic changes. Besides proliferative and regenerative limitations, endocrine cells lose their secretory capacity, contribut...

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Detalles Bibliográficos
Autores principales: Kehm, Richard, König, Jeannette, Nowotny, Kerstin, Jung, Tobias, Deubel, Stephanie, Gohlke, Sabrina, Schulz, Tim Julius, Höhn, Annika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772008/
https://www.ncbi.nlm.nih.gov/pubmed/29331666
http://dx.doi.org/10.1016/j.redox.2017.12.015