Cargando…
Age-related oxidative changes in pancreatic islets are predominantly located in the vascular system
Aged tissues usually show a decreased regenerative capacity accompanied by a decline in functionality. During aging pancreatic islets also undergo several morphological and metabolic changes. Besides proliferative and regenerative limitations, endocrine cells lose their secretory capacity, contribut...
Autores principales: | Kehm, Richard, König, Jeannette, Nowotny, Kerstin, Jung, Tobias, Deubel, Stephanie, Gohlke, Sabrina, Schulz, Tim Julius, Höhn, Annika |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772008/ https://www.ncbi.nlm.nih.gov/pubmed/29331666 http://dx.doi.org/10.1016/j.redox.2017.12.015 |
Ejemplares similares
-
Endogenous advanced glycation end products in pancreatic islets after short-term carbohydrate intervention in obese, diabetes-prone mice
por: Kehm, Richard, et al.
Publicado: (2019) -
Redox homeostasis and cell cycle activation mediate beta-cell mass expansion in aged, diabetes-prone mice under metabolic stress conditions: Role of thioredoxin-interacting protein (TXNIP)
por: Kehm, Richard, et al.
Publicado: (2020) -
Happily (n)ever after: Aging in the context of oxidative stress, proteostasis loss and cellular senescence
por: Höhn, Annika, et al.
Publicado: (2016) -
Protein oxidation - Formation mechanisms, detection and relevance as biomarkers in human diseases
por: Kehm, Richard, et al.
Publicado: (2021) -
Pancreatic Islet Cells Response to IFNγ Relies on Their Spatial Location within an Islet
por: De Burghgrave, Marine, et al.
Publicado: (2022)