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The cytosolic glyoxalases of Plasmodium falciparum are dispensable during asexual blood-stage development

The enzymes glyoxalase 1 and 2 (Glo1 and Glo2) are found in most eukaryotes and catalyze the glutathione-dependent conversion of 2-oxoaldehydes to 2-hydroxycarboxylic acids. Four glyoxalases are encoded in the genome of the malaria parasite Plasmodium falciparum, the cytosolic enzymes PfGlo1 and Pfc...

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Detalles Bibliográficos
Autores principales: Wezena, Cletus A., Alisch, Romy, Golzmann, Alexandra, Liedgens, Linda, Staudacher, Verena, Pradel, Gabriele, Deponte, Marcel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shared Science Publishers OG 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772037/
https://www.ncbi.nlm.nih.gov/pubmed/29354648
http://dx.doi.org/10.15698/mic2018.01.608