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Analysis of mitochondrial function in human induced pluripotent stem cells from patients with mitochondrial diabetes due to the A3243G mutation

We previously established human induced pluripotent stem (iPS) cells in two diabetic patients from different families with the mitochondrial A3243G mutation and isolated isogenic iPS cell clones with either undetectable or high levels of the mutation in both patients. In the present study, we analyz...

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Detalles Bibliográficos
Autores principales: Matsubara, Masaki, Kanda, Hajime, Imamura, Hiromi, Inoue, Mayumi, Noguchi, Michio, Hosoda, Kiminori, Kakizuka, Akira, Nakao, Kazuwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772054/
https://www.ncbi.nlm.nih.gov/pubmed/29343702
http://dx.doi.org/10.1038/s41598-018-19264-7