Sertraline, Paroxetine, and Chlorpromazine Are Rapidly Acting Anthelmintic Drugs Capable of Clinical Repurposing

Parasitic helminths infect over 1 billion people worldwide, while current treatments rely on a limited arsenal of drugs. To expedite drug discovery, we screened a small-molecule library of compounds with histories of use in human clinical trials for anthelmintic activity against the soil nematode Ca...

Descripción completa

Detalles Bibliográficos
Autores principales: Weeks, Janis C., Roberts, William M., Leasure, Caitlyn, Suzuki, Brian M., Robinson, Kristin J., Currey, Heather, Wangchuk, Phurpa, Eichenberger, Ramon M., Saxton, Aleen D., Bird, Thomas D., Kraemer, Brian C., Loukas, Alex, Hawdon, John M., Caffrey, Conor R., Liachko, Nicole F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772060/
https://www.ncbi.nlm.nih.gov/pubmed/29343694
http://dx.doi.org/10.1038/s41598-017-18457-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772060/
https://www.ncbi.nlm.nih.gov/pubmed/29343694
http://dx.doi.org/10.1038/s41598-017-18457-w

Ejemplares similares