Glucocerebrosidase expression patterns in the non-human primate brain

Glucocerebrosidase (GCase) is a lysosomal enzyme encoded by the GBA1 gene. Mutations in GBA1 gene lead to Gaucher’s disease, the most prevalent lysosomal storage disorder. GBA1 mutations reduce GCase activity, therefore promoting the aggregation of alpha-synuclein, a common neuropathological finding...

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Detalles Bibliográficos
Autores principales: Dopeso-Reyes, Iria G., Sucunza, Diego, Rico, Alberto J., Pignataro, Diego, Marín-Ramos, David, Roda, Elvira, Rodríguez-Pérez, Ana I., Labandeira-García, José L., Lanciego, José L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772150/
https://www.ncbi.nlm.nih.gov/pubmed/28835999
http://dx.doi.org/10.1007/s00429-017-1504-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772150/
https://www.ncbi.nlm.nih.gov/pubmed/28835999
http://dx.doi.org/10.1007/s00429-017-1504-1

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