Regulation of Signaling Pathways Involved in the Anti-proliferative and Apoptosis-inducing Effects of M22 against Non-small Cell Lung Adenocarcinoma A549 Cells

The compound 29-(4-methylpiperazine)-luepol (M22), a novel derivative of lupeol has shown anti-proliferative effects against the human non-small cell lung cancer A549 cell line. M22 showed significant anti-proliferative activity at 6.80 μM and increased accumulation of G1 cells and effectively suppr...

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Detalles Bibliográficos
Autores principales: Yuan, Yao, Wu, Jiewei, Li, Bailin, Niu, Jia, Tan, Haibo, Qiu, Shengxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772365/
https://www.ncbi.nlm.nih.gov/pubmed/29343765
http://dx.doi.org/10.1038/s41598-018-19368-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772365/
https://www.ncbi.nlm.nih.gov/pubmed/29343765
http://dx.doi.org/10.1038/s41598-018-19368-0

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