Targeting murine leukemic stem cells by antibody functionalized mesoporous silica nanoparticles

Acute leukemia is initiated and maintained by leukemia stem cells (LSCs) and therefore there is great interest to develop innovative therapeutic approaches which target LSCs. Here we show that mesoporous silica nanoparticles (MSNs) functionalized with succinic anhydride, tagged with an anti-B220 ant...

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Detalles Bibliográficos
Autores principales: Mandal, Tamoghna, Beck, Michaela, Kirsten, Nicole, Lindén, Mika, Buske, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772366/
https://www.ncbi.nlm.nih.gov/pubmed/29343865
http://dx.doi.org/10.1038/s41598-017-18932-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772366/
https://www.ncbi.nlm.nih.gov/pubmed/29343865
http://dx.doi.org/10.1038/s41598-017-18932-4

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