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Targeting murine leukemic stem cells by antibody functionalized mesoporous silica nanoparticles
Acute leukemia is initiated and maintained by leukemia stem cells (LSCs) and therefore there is great interest to develop innovative therapeutic approaches which target LSCs. Here we show that mesoporous silica nanoparticles (MSNs) functionalized with succinic anhydride, tagged with an anti-B220 ant...
Autores principales: | Mandal, Tamoghna, Beck, Michaela, Kirsten, Nicole, Lindén, Mika, Buske, Christian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772366/ https://www.ncbi.nlm.nih.gov/pubmed/29343865 http://dx.doi.org/10.1038/s41598-017-18932-4 |
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