Impact of tissue kinetic heterogeneity on PET quantification: case study with the L-[1-(11)C]leucine PET method for cerebral protein synthesis rates

Functional quantification with PET is generally based on modeling that assumes tissue regions are kinetically homogeneous. Even in regions sufficiently small to approach homogeneity, spillover due to resolution limitations of PET scanners may introduce heterogeneous kinetics into measured data. Here...

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Detalles Bibliográficos
Autores principales: Veronese, Mattia, Bertoldo, Alessandra, Tomasi, Giampaolo, Smith, Carolyn Beebe, Schmidt, Kathleen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772379/
https://www.ncbi.nlm.nih.gov/pubmed/29343731
http://dx.doi.org/10.1038/s41598-017-18890-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772379/
https://www.ncbi.nlm.nih.gov/pubmed/29343731
http://dx.doi.org/10.1038/s41598-017-18890-x

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