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Impact of tissue kinetic heterogeneity on PET quantification: case study with the L-[1-(11)C]leucine PET method for cerebral protein synthesis rates
Functional quantification with PET is generally based on modeling that assumes tissue regions are kinetically homogeneous. Even in regions sufficiently small to approach homogeneity, spillover due to resolution limitations of PET scanners may introduce heterogeneous kinetics into measured data. Here...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772379/ https://www.ncbi.nlm.nih.gov/pubmed/29343731 http://dx.doi.org/10.1038/s41598-017-18890-x |