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Galectin-13, a different prototype galectin, does not bind β-galacto-sides and forms dimers via intermolecular disulfide bridges between Cys-136 and Cys-138

During pregnancy, placental protein-13 (galectin-13) is highly expressed in the placenta and fetal tissue, and less so in maternal serum that is related to pre-eclampsia. To understand galectin-13 function at the molecular level, we solved its crystal structure and discovered that its dimer is stabi...

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Detalles Bibliográficos
Autores principales: Su, Jiyong, Wang, Yue, Si, Yunlong, Gao, Jin, Song, Chenyang, Cui, Linlin, Wu, Runjie, Tai, Guihua, Zhou, Yifa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772480/
https://www.ncbi.nlm.nih.gov/pubmed/29343868
http://dx.doi.org/10.1038/s41598-018-19465-0