Sensing Native Protein Solution Structures Using a Solid-state Nanopore: Unraveling the States of VEGF

Monitoring individual proteins in solution while simultaneously obtaining tertiary and quaternary structural information is challenging. In this study, translocation of the vascular endothelial growth factor (VEGF) protein through a solid-state nanopore (ssNP) produces distinct ion-current blockade...

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Detalles Bibliográficos
Autores principales: Varongchayakul, Nitinun, Huttner, Diana, Grinstaff, Mark W., Meller, Amit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772516/
https://www.ncbi.nlm.nih.gov/pubmed/29343861
http://dx.doi.org/10.1038/s41598-018-19332-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772516/
https://www.ncbi.nlm.nih.gov/pubmed/29343861
http://dx.doi.org/10.1038/s41598-018-19332-y

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