House dust mite induced allergic airway disease is attenuated in CD11c(cre)IL-4Rα(−/l)°(x) mice

The precise mechanisms leading to development of T helper type (Th)2-driven allergic responses are unknown. We aimed to determine how IL-4 receptor alpha (IL-4Rα) signaling on CD11c(+) cells influences allergen-induced Th2 responses in mice. CD11c(cre)IL-4Rα(−/l)°(x) mice, deficient in IL-4Rα on den...

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Detalles Bibliográficos
Autores principales: Nieuwenhuizen, Natalie Eva, Kirstein, Frank, Hoving, Jennifer Claire, Brombacher, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772663/
https://www.ncbi.nlm.nih.gov/pubmed/29343807
http://dx.doi.org/10.1038/s41598-017-19060-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772663/
https://www.ncbi.nlm.nih.gov/pubmed/29343807
http://dx.doi.org/10.1038/s41598-017-19060-9

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